New Therapeutic Targets for Type 2 Diabetes: How Metformin and GDF15 Fight High Blood Sugar
Metformin Secrets: New Targets for Type 2 Diabetes New Therapeutic Targets for Type 2 Diabetes: How Metformin and GDF15 Fight High Blood Sugar Discover the latest breakthroughs in type 2 diabetes treatment, including metformin ’s unknown mechanisms, hepatic gluconeogenesis regulation, and emerging therapeutic targets like GDF15 and TGF-β to improve glycaemic control . New therapeutic targets for type 2 diabetes: Insights into metformin and hepatic gluconeogenesis Date: June 7, 2024 Source: University of Barcelona Type 2 diabetes mellitus (T2DM) is one of the most challenging chronic diseases of the 21st century. Fasting blood sugar, or high glucose levels during fasting, is the most significant complication. Controlling it is difficult because insulin resistance leads to excessive glucose production in the liver, a process known as hepatic gluconeogenesis. This process is not yet fully scientifically understood. Type 2 Diabetes and Hepatic Gluconeogenesis: Unlocking Metformin’s Co...